【摘要】 目的 从力学的角度探讨新型的硅油基Fe3O4磁流体作为玻璃体填充物的可行性。方法 实验力学研究。首先将硅油基Fe3O4磁流体在猪眼玻璃体腔内作为填充物进行了实验，观察了硅油基Fe3O4磁流体在磁场作用下在玻璃体腔内表面的运动特性。其次将硅油基Fe3O4磁流体填充到模拟眼球内，并将模拟眼球悬挂在梯度磁场中，测出该液体的作用力。结果 硅油基Fe3O4磁流体在巩膜壁内可随磁力线方向移动并聚集。测得硅油基Fe3O4磁流体作用于模拟眼球内壁的压力为17 mmHg。结论 该硅油基Fe3O4磁流体基本上符合玻璃体填充物的要求，并具有独特的移动及定位优点。为磁性液体应用于视网膜修复提供了初步的研究及应用价值。
【关键词】 填充物； 玻璃体腔； 硅油； 磁流体； 视网膜
DOI：10.3760/cma.j.issn.1674-845X.2014.03.011
基金项目：宁波市自然科学基金（2013A610258、2013A610051）
作者单位：315040 宁波市第六医院眼科中心（龚雁、袁建树）；315800 宁波职业技术学院（王正才）；310053 杭州，浙江中医药大学信息技术学院（江依法）；315101 宁波，浙江万里学院（陆樟献）；200031 上海，复旦大学附属眼耳鼻喉科医院眼科（周行涛）
通信作者：王正才，Email：jeff_sales@cnool.net
An experimental study of silicone-based magnetic fluid implanted into the vitreous cavity
Gong Yan*， Wang Zhengcai， Jiang Yifa， Lu Zhangxian， Yuan Jianshu， Zhou Xingtao. * Ningbo No.6 Hospital， Ningbo 315040， China
Corresponding author：Wang Zhengcai，Email：jeff_sales@cnool.net
【Abstract】 Objective This paper describes a new type of silicone-oil-based Fe3O4 magnetic liquid and discusses the feasibility of vitreous implants from the mechanics viewpoint. Methods This was an experimental study. The silicone-oil-based Fe3O4 magnetic liquid had been studied previously in the pig eye cavity. The experimental results demonstrated that the silicone-oil-based Fe3O4 magnetic liquid moves on the cavity surface and aggregates at some position under the action of the magnetic field force. The silicone-oil-based Fe3O4 magnetic liquid was filled into a simulated eyeball that was suspended in a gradient magnetic field. The force applied on the simulated eyeball was measured. Results The silicone-oil-based Fe3O4 magnetic liquid moved on the simulated eye cavity surface and aggregated along the magnetic field line with an applied pressure of about 17 mmHg. Conclusion The silicone-oil-based Fe3O4 magnetic liquid approximates the vitreous implant requirements， and has unique mobile and location advantages. This provides a preliminary study approach and an estimate of usefulness for magnetic liquid used in retinal repair.
【Key words】 Stuffing； Vitreous cavity； Silicone oil； Magnetic fluids； Retina
